2022

1. Journal of Nephrology & Therapeutics – Differentiating Sodium-Glucose Cotransporter 2 Inhibitors from Live Biotherapeutic Products (Probiotics) as Novel Therapeutic Intervention to Slow CKD Progression.
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2. Journal of Nephrology & Therapeutics – The Role of Dietary Fiber and Gut Microbiome Modulation in Progression of Chronic Kidney Disease.
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2018

1.  Harvard Symposium 2018 Poster – Probiotic Supplements prevented Oxonic acid-induced Hyperuricemia and Renal Damage.
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2017

1. ASN 2017 Poster – Possible Improvements in GFR of CKD Patients with Renadyl™-3rd Biennial Survey.
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2. WCN 2017 0450 Poster – Possible Pathways of Gut Microbiome Modulation by Probiotics in Chronic Kidney Disease.
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3. WCN 2017 0453 Poster – Evaluaf-tion of the Effect of Two Mixes of Prebiotic Fibers in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®).
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2016

1. ASN 2016 poster.
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2. IPC Budapest 2016 poster.
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2015

1. Commentary: Concept and potential of Enteric Dialysis-Treating the cause not the symptom.
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2. Poster: Probiotics for CKD. The Renadyl™ story.
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3. Poster: Enteric Dialysis-Stabilization of the Gut Microbiome using Probiotics and Prebiotics (Gut-Kidney connection).
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2014

1. Randomized controlled trial of Renadyl™ in Dialysis patients.
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2. Review of Health status and level of satisfaction of customers with CKD using Renadyl™.
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3. Poster: Probiotics for CKD. The Renadyl™ story. Harvard Medical School.
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4. Poster: Probiotics for CKD. The Renadyl™ store ( Microbiome/Microbiome R&D and Business Collaboration Forum, Oct 2014 )
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5. Poster: Probiotics for CKD. The Renadyl™ store (The NewYork Academy of Sciences Dec 2014 )
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2013

1. Dose Escalation, Safety and Impact of Renadyl™_CKD-III-IV.
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2. Poster:Dose escalation, safety and impact of Renadyl™ on CKD 3 and 4 patients-Preliminary outcomes.
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3. Poster:Dose escalation, safety and impact of Renadyl™ on CKD 3 and 4 patients.
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4. Poster:Effect of Renadyl™ on NF-kB levels in hemodialysis patients.
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5. Poster:Effect of Renadyl™ on sCD30 levels in hemodialysis patients.
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6. Poster:Effect of Renadyl™ on uremic toxins in hemodialysis patient.
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2012

1. Probiotics, Prebiotics and Synbiotics: Gut and Beyond
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2. Open-Label Dose Escalation Study of Kibow® Biotics (Renadyl™) in Chronic Kidney Failure Stage III and IV Patients at Thomas Jefferson University began in May 2011 and completed on December 2012.
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3. Double-blind, randomized, placebo controlled, cross-over study of Kibow® Biotics in Chronic Kidney Failure Patients on Dialysis (Renadyl™) at SUNY-Downstate Medical Center began in April 2011 and completed on December 2012.
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2011

Two clinical trials have been initiated:

1. Observational Study of Kibow® Biotics (Renadyl™) in Chronic Kidney Failure Patients (Jefferson).
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2. Observational Study of Kibow® Biotics (Renadyl™) in Chronic Kidney Failure Patients on Dialysis (SUNY-Downstate Medical Center).
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2010

1. Poster: Probiotic Dietary Supplementation in Chronic Kidney Disease Patients (CKD III and IV) – Preliminary Observations and Combined Data Analysis of a 6-month Pilot Scale, Randomized, Double Blind and Crossover Study Design in Argentina, Canada, Nigeria and USA.
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2. Poster: Kibow®’s Pathway Through a Drug Like Validation for a Probiotic Dietary Supplement Targeted for Helping Maintain a Healthy Kidney Function
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3. Poster: Case Study of a Patient with Juvenile Diabetes and Nephropathy using a Probiotics as a Dietary Supplement for a Continuous Three Year Period
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2009

1. Poster: Dietary Supplementation with Probiotic Formulation (Kibow® Biotics) on CKD III and IV patients – a Short Term Pilot Scale Study in Canada.
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2. Editorial: “Can the bowel substitute for the kidney in advanced renal failure?
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3. Probiotic dietary supplementation in patients with stage 3 and 4 chronic kidney disease: a 6-month pilot scale trial in Canada.
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4. Poster: Probiotics for Kidney health – Gut-Based Uremic Toxin Removal – “Enteric Dialysis™”
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5. Enteric Dialysis™ – Brief introduction and its potential for CKD applications.
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2008

1. Development of Room Temperature Stable Probiotics for CKD Applications.
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2. Pilot Scale Human Clinical Trials with a Scientifically Validated Probiotic Formulation – Kibow® Biotics- With CKD Stage III and IV Patients (Mid-term and partial data analysis from Canada).
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3. Oral ingestion of probiotics and fecal analysis in CKD III and IV patients – Preliminary observations.
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2007

1. Pilot Clinical Trial of Probiotic Bacteria (Kibow® Biotics) in Chronic Kidney Disease (CKD).
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2. Progress in devising a bowel based probiotic therapy for uremia.
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2006

1. Progress in devising a bowel based probiotic therapy for uremia.
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2. In Vitro and In Vivo Assessment of Intraintestinal Bacteriotherapy in Chronic Kidney Disease.
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3. Effect of feeding Kibow® Biotics to cats and dogs in kidney failure.
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4. Preliminary clinical evaluation of Kibow® Biotics, a probiotic agent, on feline azotemia.
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2005

1. Are Clinical Trials Warranted for a Dietary Supplement with Probiotics?
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2. Initial Safety Studies of a Probiotic for Renal Insufficiency.
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3. Probiotics reduces Azotemia in Gottingen Minipigs
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4. Probiotic Amelioration of Azotemia in 5/6th Nephrectomized Sprague-Dawley Rats
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5. Short term effect of temperature on Kibow® Biotics
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6. Evaluation of Commercial Probiotic Products for Azotemia
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2004

1. An introduction to Probiotics and its potential in Clinical applications.
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2. Comparative microbial viability analysis in two delivery formats-Gel caps or mixed with food/diet.
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3. Gut-Based Uremia Therapy: In vitro R&D Investigations of an Oral Probiotic Microbial Formulation with the Aid of a Simulated Human Intestinal Microbial Ecosystem (SHIME) Biochemical Reactor.
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4. Gut-Based Uremia Therapy: Oral Bacteriotherapy Effectively Reduces Severity of Azotemia in 5/6th Nephrectomized Mini Pigs.
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5. Gut-based Uremia therapy: Continued in vitro and in vivo R&D investigations on the application of oral probiotic bacteriotherapy towards Chronic Kidney Disease (CKD) patients.
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6. Significance of dosage for effective clinical application of probiotics.
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7. Mode of Delivery and Dosage are important factors for Uremia Therapy with Probiotics
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8. Probiotic Formulation in vitro effect on Phenol and p-Cresol levels
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9. Initial Trial of Probiotic Bacteria as Therapy for Uremia in Dogs.
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10. Kibow® Biotics is preferred and superior to yogurt for uremia applications
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11. Model of Chronic Renal Failure in Miniature Pigs
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12. Oral Probiotic treatment for Uremia in a Porcine Model of Chronic Renal Failure
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13. Substitution of the kidney function by the bowel in Azotemia
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2003

1. Artificial Swallowable Kidney Formulation
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2. Oral Bacteriotherapy Effectively Reduces Severity of Azotemia in 5/6th Nephrectomized Rats
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3. Streptococcus thermophilus KB19 is a Potential component of a Probiotic Regimen Applicable in Enteric Dialysis for Uremia
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4. Rate of Urea Hydrolysis by Streptococcus thermophilus KB19 is comparable to Soil Bacterium Bacillus pasteurii and Genetically Engineered Urealytic E.coli
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5. Probiotics Extend Survival in Untreated 5/6 Nephrectomized Rats: Possible Use for Probiotics as An Adjunct in Chronic Renal Failure (CRF)®
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2002

1. Probiotics to Eliminate Nitrogenous Metabolites
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2. A Novel Synbiotic for Augmenting Kidney Function
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3. Urea Hydrolysis and Ammonia Uptake by Bacillus pasteurii
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4. Urease Activity in Commercial Yogurt
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5. Bacillus pasteurii: A Small Microbe with Huge Potential
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6. A Nutraceutical Approach to Pre-Dialysis
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7. Viability of Probiotics in Gastric Juice and Artificial Intestinal Fluid
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2001

1. Gut-Based Uremia Therapy: Simultaneously Eliminate Urea, Creatinine and Uric Acid.
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